Publications

Journal Publications
For the most up to date listing of publications, please follow our work on Google Scholar.

1. C.B. Rodell, M.S. Ahmed, C.S. Garris, M. Pittet, R. Weissleder. Development of adamantane-conjugated TLR7/8 agonists for supramolecular delivery and cancer immunotherapy. Theranostics. In Press. DOI: 10.7150/thno.35434.
2. C.B. Rodell, P.D. Koch, R. Weissleder. Screening for new macrophage therapeutics. Theranostics. 9(25), 7714-7729, 2019.
3. M.S. Ahmed*, C.B. Rodell*, M. Hulsmans, R.H. Kohler, A.D. Aguirre, M. Nahrendorf, R. Weissleder. A Supramolecular Nanocarrier for Delivery of Amiodarone Anti-Arrhythmic Therapy to the Heart. Bioconjugate Chemistry. 30(3), 733-740, 2019.
4. H.Y. Kim, R. Li, T. Ng, G. Courties, C.B. Rodell, M. Prytyskach, R.H. Kohler, M.J. Pittet, M. Nahrendorf, R. Weissleder, M. Miller. Quantitative imaging of tumor associated macrophages and their response to therapy using 64Cu- labeled Macrin. ACS Nano. 12(12): 1215-1229, 2018.
5. C.B. Rodell, S.P. Arlauckas, M.F. Cuccarese, C.S. Garris, R. Li, M.S. Ahmed, R.H. Kohler, M.J. Pittet, R. Weissleder. TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy. Nature Biomedical Engineering. 1, 2018.
Popular press & communications:
• "Behind the paper – Re-educating tumor macrophages for immunotherapy" – Nature Biomedical Engineering Community
• "Immune Cell Biology newsletter feature" – Accelerating Cancer Immunotherapy Research (ACIR)
• "Sugar Nanoparticles Reprogram Immune Cells to Help Destroy Tumors" – Medgadget
• "Cancer: Re-educating tumour-associated macrophages with nanoparticles" – Nature Reviews Drug Discovery
• "Instructing macrophages to fight cancer" – Nature Biomedical Engineering
6. Y.M. Klyachkin, C.B. Rodell, S. Ye, P. Nagareddy, A. Asfour, E. Gao, R. Annabathula, M.Z. Ratajczak, J.A Burdick, A. Abdel-Latif. Cathelicidin Related Antimicrobial Peptide (CRAMP) Enhances Bone Marrow Cell Retention and Attenuates Cardiac Dysfunction in a Mouse Model of Myocardial Infarction. Stem Cell Reviews and Reports. 14(5):702-714, 2018.
7. H. Wang, C.B. Rodell, X. Zhang, N.N. Dusaj, J.H. Gorman III, J.J. Pilla, B.M. Jackson, J.A. Burdick, R.C. Gorman, J.F. Wenk. Effects of Hydrogel Injection on Borderzone Contractility Post-Myocardial Infarction. Biomechanics and Modeling in Mechanobiology. 17(5):1533-1542, 2018.
8. L. Guo, H.J. Kim, H. Wang, J. Monaghan, J.C. Sung, Z. Diaz, N. Singh, Z.C. Zhang, E.A. Sweeny, M.E. DeSantis, M.E. Jackrel, C.B. Rodell, J.A. Burdick, A.D. Gitler, U.B. Pandey, Y.-M. Chook, J.P. Taylor, J. Shorter. Nuclear-Import Factors Reverse Aberrant Phase Transitions of Disease-Linked RNA-Binding Proteins with Prion-Like Domains. Cell. 173(3):677-692, 2018.
9. A.M. Rosales, C.B. Rodell, M.H. Chen, M.G. Morrow, K.S. Anseth, J.A. Burdick. Reversible Control of Network Properties in Azobenzene-Containing Hyaluronic Acid-Based Hydrogels. Bioconjugate Chemistry. 29(4):905–913, 2018.
10. H. Wang, C.B. Rodell, M.E. Lee, N.N. Dusaj, J.H. Gorman III, J.A. Burdick, R.C. Gorman, J.F. Wenk. Computational Sensitivity Investigation of Hydrogel Injection Characteristics for Myocardial Support. Journal of Biomechanics, 64:231-235, 2017.
11. C. Loebel*, C.B. Rodell*, M.H. Chen, J.A. Burdick. Shear-thinning and Self-healing Hydrogels as Injectable Therapeutics and for 3D-Printing. Nature Protocols, 12(8), 1521. 2017.
12. V. Ramjee, L.J. Manderfield, F. Liu, K.A. Engleka, H. Aghajanian, C.B. Rodell, W. Lu, V. Ho, T. Wang, L. Li, T. Kambayashi, J.A. Burdick, E.N. Olson, M.K. Singh, J.A. Epstein. Epicardial YAP/TAZ Orchestrate an Immune Suppressive Response following MI. Journal of Clinical Investigation, 127(3):899-911, 2017.
13. C.B. Rodell, C.B. Highley, N.N. Dusaj, J.A. Burdick. Evolution of Hierarchical Porous Structures in Supramolecular Hydrogels. Soft Matter, 12(37):7839-7847, 2016.
14. C.B. Rodell, M.E. Lee, H. Wang, S. Takebayashi, T. Takayama, T. Kawamura, J.S. Arkles, N.N. Dusaj, S.M. Dorsey, W.R.T. Witschey, J.J. Pilla, J.H. Gorman, J.F. Wenk, J.A. Burdick, R.C. Gorman. Injectable Shear-thinning Hydrogels for Minimally Invasive Delivery to Infarcted Myocardium to Limit Left-Ventricular Remodeling. Circulation: Cardiovascular Interventions, 9(10):e004058, 2016.
Popular press and communications:
• "After the heart attack: injectable gels could prevent future heart failure" – ACS Newsroom
15. C.B. Rodell, N.N. Dusaj, C.B. Highley, J.A. Burdick. Injectable and Cytocompatible Tough Double-Network Hydrogels Through Tandem Supramolecular and Covalent Crosslinking. Advanced Materials, 28(38):8419-8424, 2016.
16. L. Ouyang, C.B. Highley, C.B. Rodell, W. Sun, J.A. Burdick. 3D Printing of Shear-Thinning Hyaluronic Acid Hydrogels with Secondary Crosslinking. ACS Biomaterials Science and Engineering, 2(10):1743-1751, 2016.
17. D.E. Soranno, C.B. Rodell, C. Altman, J. Duplantis, A. Andres-Hernando, J.A. Burdick, S. Faubel. Delivery of Interleuken-10 via Injectable Hydrogels Improves Renal Outcomes and Reduces Systemic Inflammation following Ischemic Acute Kidney Injury in Mice. American Journal of Physiology – Renal Physiology, 311(2):F362-F372, 2016.
18. C.B. Rodell, J.E. Mealy, J.A. Burdick. Supramolecular Guest-Host Interactions for the Preparation of Biomedical Materials. Bioconjugate Chemistry, 26(12):2279-2289, 2015.
Popular press and communications:
• Highlighted as one of the 50 most read articles in Bioconjugate Chemistry.
• "Interview with Dr. Christopher Rodell" – Bioconjugate Chemistry social media.
19. M.W. Tibbett*, C.B. Rodell*, J.A. Burdick, K.S. Anseth. Progress in Material Design for Biomedical Applications. Proceedings of the National Academy of Sciences (PNAS), 112(47):14444-14451, 2015.
20. J.E. Mealy, C.B. Rodell, J.A. Burdick. Sustained Small Molecule Delivery from Injectable Hyaluronic Acid Hydrogels through Host-Guest Mediated Retention. Journal of Materials Chemistry B, 3(30):8010-8019, 2015.
21. A.C. Gaffey, M.H. Chen, C.M. Venkataraman, A. Trubelja, C.B. Rodell, P.V. Dinh, G. Hung, J.W. MacArthur, R.V. Soopan, J.A. Burdick, P. Atluri, Injectable Shear-thinning Hydrogels to Deliver Endothelial Progenitor Cells, Enhance Cell Engraftment, and Improve Ischemic Myocardium. The Journal of Thoracic and Cardiovascular Surgery, 150(5):1268-1277, 2015.
22. C.B. Highley, C.B. Rodell, J.A. Burdick, Direct 3D Printing of Shear-thinning Hydrogels into Self-Healing Hydrogels. Advanced Materials, 27(34):5075-5079, 2015.
23. S.M. Dorsey, M. Haris, A. Singh, W.R.T. Witschey, C.B. Rodell, F. Kogan, R. Reddy, J.A. Burdick. Visualization of Injectable Hydrogels Using Chemical Exchange Saturation Transfer MRI. ACS Biomaterials Science and Engineering, 1(4):227-237, 2015.
24. C.B. Rodell, R. Rai, S. Faubel, J.A. Burdick, D.E. Soranno. Local Immunotherapy via Delivery of Interleukin-10 and Transforming Growth Factor beta Antagonist for Treatment of Chronic Kidney Disease. Journal of Controlled Release, 206:131-139, 2015.
25. R.J. Wade, E.J. Bassin, C.B. Rodell, J.A. Burdick, Protease-Degradable Electrospun Fibrous Hydrogels. Nature Communications, 6:6639, 2015.
26. C.B. Rodell, R.J. Wade, B.P. Purcell, N. Dusaj, J.A. Burdick. Selective Proteolytic Degradation of Guest-Host Assembled, Shear-Thinning Hyaluronic Acid Hydrogels. ACS Biomaterials Science and Engineering, 1(4):277-286, 2015.
27. C.B. Rodell, J.W. MacArthur, S.M. Dorsey, R.J. Wade, Y.J. Woo, J.A. Burdick, Shear-thinning Hydrogels with Secondary Autonomous Covalent Crosslinking to Modulate Viscoelastic Properties In Vivo. Advanced Functional Materials, 25(4):636-644, 2015.
28. C.B. Rodell, J.A. Burdick. Materials Science: Radicals Promote Magnetic Gel Assembly. Nature, 514(7524), 574. 2014.
29. C.B. Highley, C.B. Rodell, I.L. Kim, R.J. Wade, J.A. Burdick, Ordered, Adherent Layers of Nanofibers Enabled by Supramolecular Interactions. Journal of Materials Chemistry B, 2(46):8110-8115, 2014.
30. C.B. Rodell, A.L. Kaminski, J.A. Burdick. Rational Design of Network Properties in Guest-Host Assembled and Shear-Thinning Hyaluronic Acid Hydrogels. Biomacromolecules, 14(11):4125-4134, 2013.
31. H.D. Lu, D.E. Soranno, C.B. Rodell, I.L. Kim, J.A. Burdick. Secondary Photocrosslinking of Injectable Shear-Thinning Dock-and-Lock Hydrogels. Advanced Healthcare Materials, 2(7):1028-1036, 2013.

* authors contributed equally
‡ manuscripts in press are available upon request

Patents

1. C.B. Rodell, R. Weissleder. Novel Macrophage Therapeutics for Immunotherapy. Application number: 62/574,942. Filed: October 20, 2017.
2. C.B. Rodell, J.A. Burdick. Stabilizing Shear-thinning Hydrogels. Patent number: 9,827,321. Issued: November 28, 2017.
3. C.B. Rodell, M.J. Moore, S.M. Grayson. Photochemically Induced Hydrogel Patterning using Photolabile Protected Reactants for Michael-type Crosslinking. Application number: 61/274,606. Filed: June 30, 2009