Journal Publications
For the most up to date listing of publications, please follow our work on Google Scholar.
- S.S. Soni, C.B. Rodell. Supramolecular Nanocarriers and Hydrogels for Macrophage-Targeted Drug Delivery. Biomedical Nanotechnology: Methods and Protocols. In Press.
- S.S. Soni, K.M. Kim, B. Sarkar, C.B. Rodell. Uptake of Cyclodextrin Nanoparticles by Macrophages is Dependent on Particle Size and Receptor-Mediated Interactions. ACS Applied Bio Materials. 2024. DOI: 10.1021/acsabm.3c00985. Link
- A.M. D’Elia, O.L. Jones, G. Canziani, B. Sarkar, I. Chaiken, C.B. Rodell. Injectable Granular Hydrogels Enable Avidity-Controlled Biotherapeutic Delivery. ACS Biomaterials Science and Engineering. VSI: ACS BMSE Early Career Investigators. 10(3): 1577-1588, 2024.Link
- BIOMED’s 2024 Student Best Paper Award Student Best Paper Award
- B. Sarkar, S.P. Arlauckas, M.F. Cuccarese, C.S. Garris, M.J. Pittet, R. Weissleder, C.B. Rodell. Host-functionalization of macrin nanoparticles to enable drug loading and control tumor-associated macrophage phenotype. Frontiers in Immunology. 15: 1331480, 2024. Link
- D.E. Soranno, C.B. Rodell. Novel Therapeutics: Can Hydrogels Work to Treat Kidney Disease? Nephron. 147(12): 769-773, 2023. (Link)
- D.S. Han, C. Erickson, K. Hansen, L. Kirkbride-Romeo, Z. He, C.B. Rodell, and D.E. Soranno. Mesenchymal stem cells delivered locally to ischemia-reperfused kidneys via injectable hyaluronic acid hydrogels reduce decrease extracellular matrix remodeling at 1 month after injury in male mice. Cells. 12(13): 1771, 2023. (Link)
- S.S. Soni, A.M. D’Elia, C.B. Rodell. Control of the post-infarct immune microenvironment through biotherapeutic and biomaterial-based approaches. Drug Delivery. and Translational Research. In Press; DOI: 10.1007/s13346-023-01290-2.(Link
- V. Turco, K. Pfleiderer, J. Hunger, N.K. Horvat, K. Karimian-Jazi, K. Schregel, M. Fischer, G. Brugnara, V. Sturm, D. Nguyen, S. Altamura, D. Agardy, K. Jähne, S.S. Soni, A. Alsasa, T. Bunse, M. Schlesner, M.U. Muckenthaler, R. Weissleder, W. Wick, S. Heiland, P. Vollmuth, M. Bendszus, C.B. Rodell, M.O. Breckwoldt, M. Platten. T cell-independent eradication of experimental glioma by intravenous TLR7/8-agonist-loaded nanoparticles. Nature Communications. 12(1): 771, 2023.Link
- S.S. Soni, A.M. D’Elia, A. Alsasa, S. Cho, T. Tylek, E. O’Brian, R. Whitaker, K.L. Spiller, C.B. Rodell. Sustained release of drug-loaded nanoparticles from injectable hydrogels enables long-term control of macrophage phenotype. Biomaterials Science. 10(24): 6951-6967, 2022.(Link)
Popular Press & Communications:
- Included in the Emerging Investigator Series, with an interview with Dr. Rodell on the Biomaterials Science Blog
- Featured on the journals back cover
- Interview with Dr. Rodell – Biomaterials Science Blog
- BIOMED’s 2023 Student Best Paper Award
- E. Garven, C.B. Rodell, K. Shema, K. Govender, S.E. Cassel, B. Ferrick, G. Kupsho, E. Kung, K.L. Spiller, R. Stevens, A.L. Throckmorton. Tunable Blood Shunt for Neonates with Complex Congenital Heart Defects. Frontiers in Bioengineering and Biotechnology. 9: 734310, 2022. (Link).
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C. Pfirschke, R. Zilionis, C. Engblom, M. Messemaker, A.E. Zou, S. Rickelt, N.A. Gort-Freitas, Y. Lin,R. Bill, M. Siwicki, J. Gungabeesoon, M.M. Sprachman, A.N. Marquard, C.B. Rodell, M.F. Cuccarese, J. Quintana, M.S. Ahmed, R.H. Kohler, V. Savova, R. Weissleder, A.M. Klein, M.J. Pittet. Macrophage-targeted therapy unlocks antitumoral crosstalk between IFN-γ-secreting lymphocytes and IL-12-producing dendritic cells. Cancer Immunology Research. 10(1): 40-55, 2022. (Link)
Popular Press & Communications:
- Pulling the Strings of the Tumor Microenvironment – Cancer Immunology Research Spotlight
- Cancer Immunology Research Spotlight – Accelerating Cancer Immunotherapy Research (ACIR)
- D.E. Soranno, L. Kirkbride-Romeo, D. Han, C. Altmann, C.B. Rodell. Measurement of glomerular filtration rate reveals that subcapsular hydrogels injection does not impair renal function. Journal of Biomedical Materials Research Part A. 110(3): 652-658, 2022. (Link)
- R. Li, T.S.C. Ng, S. Wang, M. Prytyskach, C.B. Rodell, H. Mikula, R.H. Kohler, M.A. Garlin, D.A. Lauffenburger, S. Parangi, D.M. Dinulescu, N. El-Bardeesy, R. Weissleder, M.A. Miller. Therapeutically reprogrammed nutrient signaling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer. Nature Nanotechnology. 16: 833-839, 2021. (Link)
- S.S. Soni, A. Alsasa, C.B. Rodell. Applications of Macrocyclic Supramolecules in the Immune Modulation and Therapeutic Delivery. Frontiers in Chemistry. 9, 190, 2021. (Link)
- S.S. Soni, C.B. Rodell. Polymeric Materials for Immune Engineering: Molecular Interaction to Biomaterial Design. Acta Biomaterialia. 133, 129-152, 2021.(Link).
- C.B. Rodell, P. Baldwin, B. Fernandez, R. Weissleder, S. Sridhar, J.M. Dubach. Quantification of cellular drug biodistribution addresses challenges in evaluating of in vitro and in vivo encapsulated drug delivery. Advanced Therapeutics. 4(3), 202000125, 2021. (Link).
- D.S. Li, R. Avazmohammadi, C.B. Rodell, E.W. Hsu, J.A. Burdick, J.H. Gorman III, R.C. Gorman, M. Sacks. How hydrogel inclusions modulate the local mechanical response in early and fully formed post-infarcted myocardium. Acta Biomaterialia. 114, 296-306, 2020. (Link)
- P.D. Koch, C.B. Rodell, R.H. Kohler, M.J. Pittet, R. Weissleder. Myeloid cell-targeted nanocarriers efficiently inhibit cellular inhibitor of apoptosis for cancer immunotherapy. Cell Chemical Biology. 27(1): 94-104, 2020.
- C.B. Rodell, Z.L. Zhang, N.N. Dusaj, Y. Oquendo, M.E. Lee, W. Bouma, J.H. Gorman III, J.A. Burdick, R.C. Gorman. Injectable shear-thinning hydrogels prevent ischemic mitral regurgitation and normalize ventricular flow dynamics. In Seminars in Thoracic and Cardiovascular Surgery. 32(3), 445-453, 2020.
- C.B. Rodell, M.S. Ahmed, C.S. Garris, M. Pittet, R. Weissleder. Development of adamantane-conjugated TLR7/8 agonists for supramolecular delivery and cancer immunotherapy. Theranostics. 9(26): 8426-8436, 2019.
- C.B. Rodell, P.D. Koch, R. Weissleder. Screening for new macrophage therapeutics. Theranostics. 9(25), 7714-7729, 2019.
- M.S. Ahmed*, C.B. Rodell*, M. Hulsmans, R.H. Kohler, A.D. Aguirre, M. Nahrendorf, R. Weissleder. A Supramolecular Nanocarrier for Delivery of Amiodarone Anti-Arrhythmic Therapy to the Heart. Bioconjugate Chemistry. 30(3), 733-740, 2019.
- H.Y. Kim, R. Li, T. Ng, G. Courties, C.B. Rodell, M. Prytyskach, R.H. Kohler, M.J. Pittet, M. Nahrendorf, R. Weissleder, M. Miller. Quantitative imaging of tumor associated macrophages and their response to therapy using 64Cu- labeled Macrin. ACS Nano. 12(12): 1215-1229, 2018.
- C.B. Rodell, S.P. Arlauckas, M.F. Cuccarese, C.S. Garris, R. Li, M.S. Ahmed, R.H. Kohler, M.J. Pittet, R. Weissleder. TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy. Nature Biomedical Engineering. 2(8): 578-588, 2018. Popular press & communications:
- "Behind the paper – Re-educating tumor macrophages for immunotherapy" – Nature Biomedical Engineering Community
- "Immune Cell Biology newsletter feature" – Accelerating Cancer Immunotherapy Research (ACIR)
- "Sugar Nanoparticles Reprogram Immune Cells to Help Destroy Tumors" – Medgadget
- "Cancer: Re-educating tumour-associated macrophages with nanoparticles" – Nature Reviews Drug Discovery
- "Instructing macrophages to fight cancer" – Nature Biomedical Engineering
- Y.M. Klyachkin, C.B. Rodell, S. Ye, P. Nagareddy, A. Asfour, E. Gao, R. Annabathula, M.Z. Ratajczak, J.A Burdick, A. Abdel-Latif. Cathelicidin Related Antimicrobial Peptide (CRAMP) Enhances Bone Marrow Cell Retention and Attenuates Cardiac Dysfunction in a Mouse Model of Myocardial Infarction. Stem Cell Reviews and Reports. 14(5):702-714, 2018.
- H. Wang, C.B. Rodell, X. Zhang, N.N. Dusaj, J.H. Gorman III, J.J. Pilla, B.M. Jackson, J.A. Burdick, R.C. Gorman, J.F. Wenk. Effects of Hydrogel Injection on Borderzone Contractility Post-Myocardial Infarction. Biomechanics and Modeling in Mechanobiology. 17(5):1533-1542, 2018.
- L. Guo, H.J. Kim, H. Wang, J. Monaghan, J.C. Sung, Z. Diaz, N. Singh, Z.C. Zhang, E.A. Sweeny, M.E. DeSantis, M.E. Jackrel, C.B. Rodell, J.A. Burdick, A.D. Gitler, U.B. Pandey, Y.-M. Chook, J.P. Taylor, J. Shorter. Nuclear-Import Factors Reverse Aberrant Phase Transitions of Disease-Linked RNA-Binding Proteins with Prion-Like Domains. Cell. 173(3):677-692, 2018.
- A.M. Rosales, C.B. Rodell, M.H. Chen, M.G. Morrow, K.S. Anseth, J.A. Burdick. Reversible Control of Network Properties in Azobenzene-Containing Hyaluronic Acid-Based Hydrogels. Bioconjugate Chemistry. 29(4):905–913, 2018.
- H. Wang, C.B. Rodell, M.E. Lee, N.N. Dusaj, J.H. Gorman III, J.A. Burdick, R.C. Gorman, J.F. Wenk. Computational Sensitivity Investigation of Hydrogel Injection Characteristics for Myocardial Support. Journal of Biomechanics, 64:231-235, 2017.
- C. Loebel*, C.B. Rodell*, M.H. Chen, J.A. Burdick. Shear-thinning and Self-healing Hydrogels as Injectable Therapeutics and for 3D-Printing. Nature Protocols, 12(8), 1521. 2017.
- V. Ramjee, L.J. Manderfield, F. Liu, K.A. Engleka, H. Aghajanian, C.B. Rodell, W. Lu, V. Ho, T. Wang, L. Li, T. Kambayashi, J.A. Burdick, E.N. Olson, M.K. Singh, J.A. Epstein. Epicardial YAP/TAZ Orchestrate an Immune Suppressive Response following MI. Journal of Clinical Investigation, 127(3):899-911, 2017.
- C.B. Rodell, C.B. Highley, N.N. Dusaj, J.A. Burdick. Evolution of Hierarchical Porous Structures in Supramolecular Hydrogels. Soft Matter, 12(37):7839-7847, 2016.
- C.B. Rodell, M.E. Lee, H. Wang, S. Takebayashi, T. Takayama, T. Kawamura, J.S. Arkles, N.N. Dusaj, S.M. Dorsey, W.R.T. Witschey, J.J. Pilla, J.H. Gorman, J.F. Wenk, J.A. Burdick, R.C. Gorman. Injectable Shear-thinning Hydrogels for Minimally Invasive Delivery to Infarcted Myocardium to Limit Left-Ventricular Remodeling. Circulation: Cardiovascular Interventions, 9(10):e004058, 2016. Popular press and communications:
- C.B. Rodell, N.N. Dusaj, C.B. Highley, J.A. Burdick. Injectable and Cytocompatible Tough Double-Network Hydrogels Through Tandem Supramolecular and Covalent Crosslinking. Advanced Materials, 28(38):8419-8424, 2016.
- L. Ouyang, C.B. Highley, C.B. Rodell, W. Sun, J.A. Burdick. 3D Printing of Shear-Thinning Hyaluronic Acid Hydrogels with Secondary Crosslinking. ACS Biomaterials Science and Engineering, 2(10):1743-1751, 2016.
- D.E. Soranno, C.B. Rodell, C. Altman, J. Duplantis, A. Andres-Hernando, J.A. Burdick, S. Faubel. Delivery of Interleuken-10 via Injectable Hydrogels Improves Renal Outcomes and Reduces Systemic Inflammation following Ischemic Acute Kidney Injury in Mice. American Journal of Physiology – Renal Physiology, 311(2):F362-F372, 2016.
- C.B. Rodell, J.E. Mealy, J.A. Burdick. Supramolecular Guest-Host Interactions for the Preparation of Biomedical Materials. Bioconjugate Chemistry, 26(12):2279-2289, 2015. Popular press and communications:
- Highlighted as one of the 50 most read articles in Bioconjugate Chemistry.
- "Interview with Dr. Christopher Rodell" – Bioconjugate Chemistry social media.
- M.W. Tibbett*, C.B. Rodell*, J.A. Burdick, K.S. Anseth. Progress in Material Design for Biomedical Applications. Proceedings of the National Academy of Sciences (PNAS), 112(47):14444-14451, 2015.
- J.E. Mealy, C.B. Rodell, J.A. Burdick. Sustained Small Molecule Delivery from Injectable Hyaluronic Acid Hydrogels through Host-Guest Mediated Retention. Journal of Materials Chemistry B, 3(30):8010-8019, 2015.
- A.C. Gaffey, M.H. Chen, C.M. Venkataraman, A. Trubelja, C.B. Rodell, P.V. Dinh, G. Hung, J.W. MacArthur, R.V. Soopan, J.A. Burdick, P. Atluri, Injectable Shear-thinning Hydrogels to Deliver Endothelial Progenitor Cells, Enhance Cell Engraftment, and Improve Ischemic Myocardium. The Journal of Thoracic and Cardiovascular Surgery, 150(5):1268-1277, 2015.
- C.B. Highley, C.B. Rodell, J.A. Burdick, Direct 3D Printing of Shear-thinning Hydrogels into Self-Healing Hydrogels. Advanced Materials, 27(34):5075-5079, 2015.
- S.M. Dorsey, M. Haris, A. Singh, W.R.T. Witschey, C.B. Rodell, F. Kogan, R. Reddy, J.A. Burdick. Visualization of Injectable Hydrogels Using Chemical Exchange Saturation Transfer MRI. ACS Biomaterials Science and Engineering, 1(4):227-237, 2015.
- C.B. Rodell, R. Rai, S. Faubel, J.A. Burdick, D.E. Soranno. Local Immunotherapy via Delivery of Interleukin-10 and Transforming Growth Factor beta Antagonist for Treatment of Chronic Kidney Disease. Journal of Controlled Release, 206:131-139, 2015.
- R.J. Wade, E.J. Bassin, C.B. Rodell, J.A. Burdick, Protease-Degradable Electrospun Fibrous Hydrogels. Nature Communications, 6:6639, 2015.
- C.B. Rodell, R.J. Wade, B.P. Purcell, N. Dusaj, J.A. Burdick. Selective Proteolytic Degradation of Guest-Host Assembled, Shear-Thinning Hyaluronic Acid Hydrogels. ACS Biomaterials Science and Engineering, 1(4):277-286, 2015.
- C.B. Rodell, J.W. MacArthur, S.M. Dorsey, R.J. Wade, Y.J. Woo, J.A. Burdick, Shear-thinning Hydrogels with Secondary Autonomous Covalent Crosslinking to Modulate Viscoelastic Properties In Vivo. Advanced Functional Materials, 25(4):636-644, 2015.
- C.B. Highley, C.B. Rodell, I.L. Kim, R.J. Wade, J.A. Burdick, Ordered, Adherent Layers of Nanofibers Enabled by Supramolecular Interactions. Journal of Materials Chemistry B, 2(46):8110-8115, 2014.
- C.B. Rodell, A.L. Kaminski, J.A. Burdick. Rational Design of Network Properties in Guest-Host Assembled and Shear-Thinning Hyaluronic Acid Hydrogels. Biomacromolecules, 14(11):4125-4134, 2013.
- H.D. Lu, D.E. Soranno, C.B. Rodell, I.L. Kim, J.A. Burdick. Secondary Photocrosslinking of Injectable Shear-Thinning Dock-and-Lock Hydrogels. Advanced Healthcare Materials, 2(7):1028-1036, 2013.
Popular press, communications, & awards:
* authors contributed equally
‡ manuscripts in press are available upon request