Journal Publications

For the most up to date listing of publications, please follow our work on Google Scholar.

  1. S.S. Soni, C.B. Rodell. Supramolecular Nanocarriers and Hydrogels for Macrophage-Targeted Drug Delivery. Biomedical Nanotechnology: Methods and Protocols. In Press.
  2. S.S. Soni, K.M. Kim, B. Sarkar, C.B. Rodell. Uptake of Cyclodextrin Nanoparticles by Macrophages is Dependent on Particle Size and Receptor-Mediated Interactions. ACS Applied Bio Materials. 2024. DOI: 10.1021/acsabm.3c00985. Link
  3. A.M. D’Elia, O.L. Jones, G. Canziani, B. Sarkar, I. Chaiken, C.B. Rodell. Injectable Granular Hydrogels Enable Avidity-Controlled Biotherapeutic Delivery. ACS Biomaterials Science and Engineering. VSI: ACS BMSE Early Career Investigators. 10(3): 1577-1588, 2024.Link
  4. Popular press, communications, & awards:

  5. B. Sarkar, S.P. Arlauckas, M.F. Cuccarese, C.S. Garris, M.J. Pittet, R. Weissleder, C.B. Rodell. Host-functionalization of macrin nanoparticles to enable drug loading and control tumor-associated macrophage phenotype. Frontiers in Immunology. 15: 1331480, 2024. Link
  6. D.E. Soranno, C.B. Rodell. Novel Therapeutics: Can Hydrogels Work to Treat Kidney Disease? Nephron. 147(12): 769-773, 2023. (Link)
  7. D.S. Han, C. Erickson, K. Hansen, L. Kirkbride-Romeo, Z. He, C.B. Rodell, and D.E. Soranno. Mesenchymal stem cells delivered locally to ischemia-reperfused kidneys via injectable hyaluronic acid hydrogels reduce decrease extracellular matrix remodeling at 1 month after injury in male mice. Cells. 12(13): 1771, 2023. (Link)
  8. S.S. Soni, A.M. D’Elia, C.B. Rodell. Control of the post-infarct immune microenvironment through biotherapeutic and biomaterial-based approaches. Drug Delivery. and Translational Research. In Press; DOI: 10.1007/s13346-023-01290-2.(Link
  9. V. Turco, K. Pfleiderer, J. Hunger, N.K. Horvat, K. Karimian-Jazi, K. Schregel, M. Fischer, G. Brugnara, V. Sturm, D. Nguyen, S. Altamura, D. Agardy, K. Jähne, S.S. Soni, A. Alsasa, T. Bunse, M. Schlesner, M.U. Muckenthaler, R. Weissleder, W. Wick, S. Heiland, P. Vollmuth, M. Bendszus, C.B. Rodell, M.O. Breckwoldt, M. Platten. T cell-independent eradication of experimental glioma by intravenous TLR7/8-agonist-loaded nanoparticles. Nature Communications. 12(1): 771, 2023.Link
  10. S.S. Soni, A.M. D’Elia, A. Alsasa, S. Cho, T. Tylek, E. O’Brian, R. Whitaker, K.L. Spiller, C.B. Rodell. Sustained release of drug-loaded nanoparticles from injectable hydrogels enables long-term control of macrophage phenotype. Biomaterials Science. 10(24): 6951-6967, 2022.(Link)

    Popular Press & Communications:

  11. E. Garven, C.B. Rodell, K. Shema, K. Govender, S.E. Cassel, B. Ferrick, G. Kupsho, E. Kung, K.L. Spiller, R. Stevens, A.L. Throckmorton. Tunable Blood Shunt for Neonates with Complex Congenital Heart Defects. Frontiers in Bioengineering and Biotechnology. 9: 734310, 2022. (Link).
  12. C. Pfirschke, R. Zilionis, C. Engblom, M. Messemaker, A.E. Zou, S. Rickelt, N.A. Gort-Freitas, Y. Lin,R. Bill, M. Siwicki, J. Gungabeesoon, M.M. Sprachman, A.N. Marquard, C.B. Rodell, M.F. Cuccarese, J. Quintana, M.S. Ahmed, R.H. Kohler, V. Savova, R. Weissleder, A.M. Klein, M.J. Pittet. Macrophage-targeted therapy unlocks antitumoral crosstalk between IFN-γ-secreting lymphocytes and IL-12-producing dendritic cells. Cancer Immunology Research. 10(1): 40-55, 2022. (Link)

    Popular Press & Communications:

  13. D.E. Soranno, L. Kirkbride-Romeo, D. Han, C. Altmann, C.B. Rodell. Measurement of glomerular filtration rate reveals that subcapsular hydrogels injection does not impair renal function. Journal of Biomedical Materials Research Part A. 110(3): 652-658, 2022. (Link)
  14. R. Li, T.S.C. Ng, S. Wang, M. Prytyskach, C.B. Rodell, H. Mikula, R.H. Kohler, M.A. Garlin, D.A. Lauffenburger, S. Parangi, D.M. Dinulescu, N. El-Bardeesy, R. Weissleder, M.A. Miller. Therapeutically reprogrammed nutrient signaling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer. Nature Nanotechnology. 16: 833-839, 2021. (Link)
  15. S.S. Soni, A. Alsasa, C.B. Rodell. Applications of Macrocyclic Supramolecules in the Immune Modulation and Therapeutic Delivery. Frontiers in Chemistry. 9, 190, 2021. (Link)
  16. S.S. Soni, C.B. Rodell. Polymeric Materials for Immune Engineering: Molecular Interaction to Biomaterial Design. Acta Biomaterialia. 133, 129-152, 2021.(Link).
  17. C.B. Rodell, P. Baldwin, B. Fernandez, R. Weissleder, S. Sridhar, J.M. Dubach. Quantification of cellular drug biodistribution addresses challenges in evaluating of in vitro and in vivo encapsulated drug delivery. Advanced Therapeutics. 4(3), 202000125, 2021. (Link).
  18. D.S. Li, R. Avazmohammadi, C.B. Rodell, E.W. Hsu, J.A. Burdick, J.H. Gorman III, R.C. Gorman, M. Sacks. How hydrogel inclusions modulate the local mechanical response in early and fully formed post-infarcted myocardium. Acta Biomaterialia. 114, 296-306, 2020. (Link)
  19. P.D. Koch, C.B. Rodell, R.H. Kohler, M.J. Pittet, R. Weissleder. Myeloid cell-targeted nanocarriers efficiently inhibit cellular inhibitor of apoptosis for cancer immunotherapy. Cell Chemical Biology. 27(1): 94-104, 2020.
  20. C.B. Rodell, Z.L. Zhang, N.N. Dusaj, Y. Oquendo, M.E. Lee, W. Bouma, J.H. Gorman III, J.A. Burdick, R.C. Gorman. Injectable shear-thinning hydrogels prevent ischemic mitral regurgitation and normalize ventricular flow dynamics. In Seminars in Thoracic and Cardiovascular Surgery. 32(3), 445-453, 2020.
  21. C.B. Rodell, M.S. Ahmed, C.S. Garris, M. Pittet, R. Weissleder. Development of adamantane-conjugated TLR7/8 agonists for supramolecular delivery and cancer immunotherapy. Theranostics. 9(26): 8426-8436, 2019.
  22. C.B. Rodell, P.D. Koch, R. Weissleder. Screening for new macrophage therapeutics. Theranostics. 9(25), 7714-7729, 2019.
  23. M.S. Ahmed*, C.B. Rodell*, M. Hulsmans, R.H. Kohler, A.D. Aguirre, M. Nahrendorf, R. Weissleder. A Supramolecular Nanocarrier for Delivery of Amiodarone Anti-Arrhythmic Therapy to the Heart. Bioconjugate Chemistry. 30(3), 733-740, 2019.
  24. H.Y. Kim, R. Li, T. Ng, G. Courties, C.B. Rodell, M. Prytyskach, R.H. Kohler, M.J. Pittet, M. Nahrendorf, R. Weissleder, M. Miller. Quantitative imaging of tumor associated macrophages and their response to therapy using 64Cu- labeled Macrin. ACS Nano. 12(12): 1215-1229, 2018.
  25. C.B. Rodell, S.P. Arlauckas, M.F. Cuccarese, C.S. Garris, R. Li, M.S. Ahmed, R.H. Kohler, M.J. Pittet, R. Weissleder. TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy. Nature Biomedical Engineering. 2(8): 578-588, 2018.
  26. Popular press & communications:
  27. Y.M. Klyachkin, C.B. Rodell, S. Ye, P. Nagareddy, A. Asfour, E. Gao, R. Annabathula, M.Z. Ratajczak, J.A Burdick, A. Abdel-Latif. Cathelicidin Related Antimicrobial Peptide (CRAMP) Enhances Bone Marrow Cell Retention and Attenuates Cardiac Dysfunction in a Mouse Model of Myocardial Infarction. Stem Cell Reviews and Reports. 14(5):702-714, 2018.
  28. H. Wang, C.B. Rodell, X. Zhang, N.N. Dusaj, J.H. Gorman III, J.J. Pilla, B.M. Jackson, J.A. Burdick, R.C. Gorman, J.F. Wenk. Effects of Hydrogel Injection on Borderzone Contractility Post-Myocardial Infarction. Biomechanics and Modeling in Mechanobiology. 17(5):1533-1542, 2018.
  29. L. Guo, H.J. Kim, H. Wang, J. Monaghan, J.C. Sung, Z. Diaz, N. Singh, Z.C. Zhang, E.A. Sweeny, M.E. DeSantis, M.E. Jackrel, C.B. Rodell, J.A. Burdick, A.D. Gitler, U.B. Pandey, Y.-M. Chook, J.P. Taylor, J. Shorter. Nuclear-Import Factors Reverse Aberrant Phase Transitions of Disease-Linked RNA-Binding Proteins with Prion-Like Domains. Cell. 173(3):677-692, 2018.
  30. A.M. Rosales, C.B. Rodell, M.H. Chen, M.G. Morrow, K.S. Anseth, J.A. Burdick. Reversible Control of Network Properties in Azobenzene-Containing Hyaluronic Acid-Based Hydrogels. Bioconjugate Chemistry. 29(4):905–913, 2018.
  31. H. Wang, C.B. Rodell, M.E. Lee, N.N. Dusaj, J.H. Gorman III, J.A. Burdick, R.C. Gorman, J.F. Wenk. Computational Sensitivity Investigation of Hydrogel Injection Characteristics for Myocardial Support. Journal of Biomechanics, 64:231-235, 2017.
  32. C. Loebel*, C.B. Rodell*, M.H. Chen, J.A. Burdick. Shear-thinning and Self-healing Hydrogels as Injectable Therapeutics and for 3D-Printing. Nature Protocols, 12(8), 1521. 2017.
  33. V. Ramjee, L.J. Manderfield, F. Liu, K.A. Engleka, H. Aghajanian, C.B. Rodell, W. Lu, V. Ho, T. Wang, L. Li, T. Kambayashi, J.A. Burdick, E.N. Olson, M.K. Singh, J.A. Epstein. Epicardial YAP/TAZ Orchestrate an Immune Suppressive Response following MI. Journal of Clinical Investigation, 127(3):899-911, 2017.
  34. C.B. Rodell, C.B. Highley, N.N. Dusaj, J.A. Burdick. Evolution of Hierarchical Porous Structures in Supramolecular Hydrogels. Soft Matter, 12(37):7839-7847, 2016.
  35. C.B. Rodell, M.E. Lee, H. Wang, S. Takebayashi, T. Takayama, T. Kawamura, J.S. Arkles, N.N. Dusaj, S.M. Dorsey, W.R.T. Witschey, J.J. Pilla, J.H. Gorman, J.F. Wenk, J.A. Burdick, R.C. Gorman. Injectable Shear-thinning Hydrogels for Minimally Invasive Delivery to Infarcted Myocardium to Limit Left-Ventricular Remodeling. Circulation: Cardiovascular Interventions, 9(10):e004058, 2016.
  36. Popular press and communications:
  37. C.B. Rodell, N.N. Dusaj, C.B. Highley, J.A. Burdick. Injectable and Cytocompatible Tough Double-Network Hydrogels Through Tandem Supramolecular and Covalent Crosslinking. Advanced Materials, 28(38):8419-8424, 2016.
  38. L. Ouyang, C.B. Highley, C.B. Rodell, W. Sun, J.A. Burdick. 3D Printing of Shear-Thinning Hyaluronic Acid Hydrogels with Secondary Crosslinking. ACS Biomaterials Science and Engineering, 2(10):1743-1751, 2016.
  39. D.E. Soranno, C.B. Rodell, C. Altman, J. Duplantis, A. Andres-Hernando, J.A. Burdick, S. Faubel. Delivery of Interleuken-10 via Injectable Hydrogels Improves Renal Outcomes and Reduces Systemic Inflammation following Ischemic Acute Kidney Injury in Mice. American Journal of Physiology – Renal Physiology, 311(2):F362-F372, 2016.
  40. C.B. Rodell, J.E. Mealy, J.A. Burdick. Supramolecular Guest-Host Interactions for the Preparation of Biomedical Materials. Bioconjugate Chemistry, 26(12):2279-2289, 2015.
  41. Popular press and communications:
  42. M.W. Tibbett*, C.B. Rodell*, J.A. Burdick, K.S. Anseth. Progress in Material Design for Biomedical Applications. Proceedings of the National Academy of Sciences (PNAS), 112(47):14444-14451, 2015.
  43. J.E. Mealy, C.B. Rodell, J.A. Burdick. Sustained Small Molecule Delivery from Injectable Hyaluronic Acid Hydrogels through Host-Guest Mediated Retention. Journal of Materials Chemistry B, 3(30):8010-8019, 2015.
  44. A.C. Gaffey, M.H. Chen, C.M. Venkataraman, A. Trubelja, C.B. Rodell, P.V. Dinh, G. Hung, J.W. MacArthur, R.V. Soopan, J.A. Burdick, P. Atluri, Injectable Shear-thinning Hydrogels to Deliver Endothelial Progenitor Cells, Enhance Cell Engraftment, and Improve Ischemic Myocardium. The Journal of Thoracic and Cardiovascular Surgery, 150(5):1268-1277, 2015.
  45. C.B. Highley, C.B. Rodell, J.A. Burdick, Direct 3D Printing of Shear-thinning Hydrogels into Self-Healing Hydrogels. Advanced Materials, 27(34):5075-5079, 2015.
  46. S.M. Dorsey, M. Haris, A. Singh, W.R.T. Witschey, C.B. Rodell, F. Kogan, R. Reddy, J.A. Burdick. Visualization of Injectable Hydrogels Using Chemical Exchange Saturation Transfer MRI. ACS Biomaterials Science and Engineering, 1(4):227-237, 2015.
  47. C.B. Rodell, R. Rai, S. Faubel, J.A. Burdick, D.E. Soranno. Local Immunotherapy via Delivery of Interleukin-10 and Transforming Growth Factor beta Antagonist for Treatment of Chronic Kidney Disease. Journal of Controlled Release, 206:131-139, 2015.
  48. R.J. Wade, E.J. Bassin, C.B. Rodell, J.A. Burdick, Protease-Degradable Electrospun Fibrous Hydrogels. Nature Communications, 6:6639, 2015.
  49. C.B. Rodell, R.J. Wade, B.P. Purcell, N. Dusaj, J.A. Burdick. Selective Proteolytic Degradation of Guest-Host Assembled, Shear-Thinning Hyaluronic Acid Hydrogels. ACS Biomaterials Science and Engineering, 1(4):277-286, 2015.
  50. C.B. Rodell, J.W. MacArthur, S.M. Dorsey, R.J. Wade, Y.J. Woo, J.A. Burdick, Shear-thinning Hydrogels with Secondary Autonomous Covalent Crosslinking to Modulate Viscoelastic Properties In Vivo. Advanced Functional Materials, 25(4):636-644, 2015.
  51. C.B. Highley, C.B. Rodell, I.L. Kim, R.J. Wade, J.A. Burdick, Ordered, Adherent Layers of Nanofibers Enabled by Supramolecular Interactions. Journal of Materials Chemistry B, 2(46):8110-8115, 2014.
  52. C.B. Rodell, A.L. Kaminski, J.A. Burdick. Rational Design of Network Properties in Guest-Host Assembled and Shear-Thinning Hyaluronic Acid Hydrogels. Biomacromolecules, 14(11):4125-4134, 2013.
  53. H.D. Lu, D.E. Soranno, C.B. Rodell, I.L. Kim, J.A. Burdick. Secondary Photocrosslinking of Injectable Shear-Thinning Dock-and-Lock Hydrogels. Advanced Healthcare Materials, 2(7):1028-1036, 2013.
  54. * authors contributed equally
    ‡ manuscripts in press are available upon request