Poly(Lactic Acid) Ultrasound Contrast Agents

Polymeric microspheres for diagnostic ultrasound imaging and targeted drug delivery.


Controlled Drug Delivery

Confocal microscopy image showing successful encapsulation of chemotherapeutic drugs within ultrasound contrast agent polymeric shells.


Encapsulated Cells for Spinal Cord Regeneration

Encapsulation of genetically engineered cells for treatment of spinal cord injuries.

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Surfactant Based Ultrasound Contrast Agent

Enhanced 3-D image of a rabbit kidney using surfactant based contrast agent.

Our work combines materials science, drug delivery, and ultrasound…

Our work is at the interface of biotechnology and materials science. A major focus is the study and development of polymers to deliver drugs, particularly genetically engineered proteins, DNA and RNAi, continuously at controlled rates for prolonged periods of time. Work is in progress in the following areas:


nvestigating the mechanism of release from polymeric delivery systems with concomitant microstructural analysis and mathematical modeling.


tudying applications of these systems including the development of effective long-term delivery systems for insulin, anti-cancer drugs, growth factors, gene therapy agents and vaccines.


eveloping controlled release systems that can be magnetically, ultrasonically, or enzymatically triggered to increase release rates.

We Are...


...a diverse group of scientists and engineers with interests spanning molecular and cell biophysics and polymer engineering. Among our latest studies are controlling stem cell differentiation with materials, shrinking tumors with drug-loaded polymersomes and worm micelles, developing new polymers for both purposes, and single molecules studies of protein folding.

For more details about the lab and our work, please browse the links in navigation bar on the top.

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