W. Rose, A.L. Throckmorton, B. Heintzelman, and V. Tchantchaleishvili. “Impact of Continuous-Flow Mechanical Circulatory Support on Cerebrospinal Fluid Motility.” Artificial Organs 2023, In press.
M.D. Hirschhorn, J.E. Lawley, A.J. Roof, A.P.T. Johnson, W.A. Stoddard, R. Stevens, F. Arabia, V. Tchantchaleishvili, S.W. Day, and A.L. Throckmorton. “Next Generation Development of Hybrid Continuous Flow Pediatric Circulatory Assist Device: Design-Build-Test.” ASAIO J 2023, In press.
M. Hirschhorn, N. Catucci, S. Day, R. Stevens, V. Tchantchaleishvili, and A.L. Throckmorton. “Channel Impeller Design for Centrifugal Blood Pump in Hybrid Pediatric Total Artificial Heart: Modeling, Magnet Integration, and Hydraulic Experiments.” Artificial Organs 2023, In press.
2022
S.G. Chopski, K. Govender, A. May, E. Garven, R.M. Stevens, V. Tchantchaleishvili, and A.L. Throckmorton. “Novel Hybrid Total Artificial Heart with Integrated Oxygenator.” Journal of Cardiac Surgery 2022; 37(12): 5172-5186.
J.S. Gordon, C.M. Blazoski, C.T. Wood, C. Zuber, H.T. Massey, A.L. Throckmorton, and V. Tchantchaleishvili. “Mechanical and Interventional Support for Heart Failure with Preserved Ejection Fraction: A Review.” Artificial Organs 2022; 46(11): 2109-2117.
C.S. Fox, T.C. Palazzolo, M. Hirschhorn, R.M. Stevens, J. Rossano, S.W. Day, V. Tchantchaleishvili, and A.L. Throckmorton. “Development of the Centrifugal Blood Pump for a Hybrid Continuous-Flow Pediatric Total Artificial Heart: Model, Make, Measure.” Frontiers in Cardiovascular Medicine 2022; 4(9): 886874.
C.C. Do-Nguyen, A.L. Throckmorton, and R.M. Stevens. “Total anomalous pulmonary venous connection remains a challenging pediatric disease.” J Cardiac Surgery 2022; 37(10): 2988-2990.
T. Palazzolo, M.D. Hirschhorn, E. Garven, S. Day, R. Stevens, J. Rossano, V. Tchantchaleishvili, and A.L. Throckmorton. “Technology Landscape of Pediatric Mechanical Circulatory Support Devices – A Systematic Review 2010-2021.” Artificial Organs 2022; 46(8):1475-1490.
E.E. Garven, C. Rodell, K. Shema, K. Govender, S.E. Cassel, B. Ferrick, G. Kupsho, E. Kung, K. Spiller, R. Stevens, and A.L. Throckmorton. “Tunable Blood Shunt for Neonates with Complex Congenital Heart Defects.” Frontiers in Bioengineering and Biotechnology 2022; 9: 734310.
Z. Chen, H. Zhao, Y. Zhao, J. Han, X. Yang, A.L. Throckmorton, Z. Wei, S. Ge, and Y. He. “Retrograde Flow in Aortic Isthmus in Normal and Fetal Heart Disease by Principal Component Analysis and Computational Fluid Dynamics.” Echocardiography 2022; 39(2):166-177.
R. Stevens, J. Sun, A.L. Throckmorton, E. Garven, and E. Poletto. “Essential Role of Cardiac Computed Tomography for Surgical Decision Making in Children with Total Anomalous Pulmonary Venous Connection and Single Ventricle.” J Cardiac Surgery 2022; 37(7): 2166-2167.
S.R. Cook, H.B. Musgrove, A.L. Throckmorton, and R.R. Pompano. “Microscale impeller pump for recirculating flow in organs-on-chip and microreactors.” Lab-on-a-Chip 2022; 22: 605-620. DOI: 10.1039/D1LC01081F.
2021
R. Stevens, J. Sun, L. Mulinari, J. Chilingerian, A.L. Throckmorton, and R. Latifi. “Invited Commentary: A prospective randomized trial on parents’ disease knowledge and quality of life. Shall WeChat about Patient Related Outcomes (PRO)?” J Cardiac Surgery (IF 1.62) 2021; 36(10): 3698-3701.
R. Stevens, J. Sun, A.L. Throckmorton, L. Mulinari, and R. Latifi. “Invited Commentary: Multi-disciplinary Frameworks for the Treatment of Primary Cardiac Sarcoma.” J Cardiac Surgery (IF 1.62) 2021; 36(9): 3456-3457.
C.C. Do-Nguyen, R.M. Stevens, J.O. Gautier, A.L. Throckmorton, and L. Mulinari. “Invited Commentary: Asymmetric Dimethylarginine (ADMA): Is it a risk factor in the repair of aortic coarctation?” J Cardiac Surgery (IF 1.62) 2021; 6(8): 2741-2742.
A.L. Throckmorton, E.J. Bass, B. Ferrick, A. Ramakrishnan, S. Eichmann, N. Catucci, B. Eshelman, J. McNamara, E. Sundquist, N. Beatson, M. Hirschhorn*, P. Menon**, B. Datner, R. Stevens, and M. Marcolongo. “A Cross-Community COVID-19 Leadership Rapid-Response Effort: Design-Build of Drexel AJ Flex Face Shields.” Annals of Biomedical Engineering (IF 3.324) 2021; 49: 950-958.
R. Stevens, A.L. Throckmorton, and L. Mulinari. “Invited Commentary: Modified Technique for Coarctation of the Aorta with hypoplastic distal aortic arch; a keystone shift away from the archway?” J Cardiac Surgery (IF 1.62) 2021; 36(6): 2070-2071.
M. Hirschhorn*, E. Garven, J.L. Wells, R. Stevens, V. Tchantchaleishvili, and A.L. Throckmorton. “The Newly Emerging Field of Pediatric Engineering: Innovation for Our Next Generation.” Artificial Organs (IF 3.094) 2021; 45(6): 537-541.
C.M. Komlo, A.L. Throckmorton, and V. Tchantchaleishvili. “On the Path to the permanent artificial heart technology: Greater energy independence is paramount.” Artificial Organs (IF 3.094) 2021; 45(4): 332-335.
A.L. Throckmorton, E.E. Garven, M. Hirschhorn, S.W. Day, R. Stevens, and V. Tchantchaleishvili. “Forward-Thinking Design Solutions for Mechanical Circulatory Support: Multifunctional Hybrid Continuous-Flow VAD Technology.” Annals of Cardiothoracic Surgery (IF 4.01) 2021; 10(3): 383-385.
H. Sarkisyan, R. Stevens, V. Tchantchaleishvili, F. Arabia, and A.L. Throckmorton. “Integrated Long-term Multifunctional Pediatric Mechanical Circulatory Assist Device.” Artificial Organs (IF 3.094) 2021; 45(5): E65-E78.
2020
J.S. Gordon, C.T. Wood, J.G. Luc, R.A. Watson, E.J. Maynes, J.H. Choi, R.J. Morris, H.T. Massey, A.L. Throckmorton, and V. Tchantchaleishvili. “Clinical Implications of Lactate Dehydrogenase Isoenzymes in Hemolysis and Continuous-flow Left Ventricular Assist Device-Induced Thrombosis.” Artificial Organs (IF 3.094) 2020; 44(3): 231-238.
R. M. Stevens, M. Kilcoyne, C. Do-Nguyen, V. Mahan, and A.L. Throckmorton. “Deep Hypothermic Circulatory Arrest and Cardiopulmonary Bypass.” Medscape 2020: 1-18.
M. Hirschhorn, E. Bisirri, R. Stevens, and A.L. Throckmorton. “Fluid-Structure Interaction Analysis of a Collapsible Axial Flow Blood Pump and Protective Cage for Fontan Patients.” Artificial Organs (IF 3.094) 2020; 44(8): E337-E347.
M. Hirschhorn, V. Tchantchaleishvili, R. Stevens, J. Rossano, and A.L. Throckmorton. “Fluid-Structure Interaction Modeling in Cardiovascular Medicine – A Systematic Review: 2017-2019.” Med Eng Phys (IF 1.737) 2020; 78: 1-13.
E. Garven and A.L. Throckmorton. “Personalized Surgical Planning by Computational and Visual Methods in 21st Century Medical Engineering.” J Cardiac Surgery (IF 1.62) 2020; 35(3): 526-527.
J.S. Gordon, C.T. Wood, J.G. Luc, R.A. Watson, E.J. Maynes, J.H. Choi, R.J. Morris, H.T. Massey, A.L. Throckmorton, and V. Tchantchaleishvili. “Clinical Implications of Lactate Dehydrogenase Isoenzymes in Hemolysis and Continuous-flow Left Ventricular Assist Device-Induced Thrombosis.” Artificial Organs (IF 3.094) 2020; 44(3): 231-238.
2019
C.S. Fox, H. Sarkisyan, R. Stevens, F. Arabia, W. Fischer, J. Rossano, and A.L. Throckmorton. “New Versatile Dual-Support Pediatric Heart Pump.” Artificial Organs 2019;43(11):1055-1064.
M. Hirschhorn and A.L. Throckmorton. “Pediatric Mechanical Circulatory Support – Leveraging Design Innovation for the Younger Generation.” J Cardiac Surgery 2019; 1-3.
S.G. Chopski, K.K. Whitehead, G.J. Englehardt, and A.L. Throckmorton. “Cardiac Magnetic Resonance Imaging of Mechanical Cavopulmonary Assistance." J Medical Devices 2019; 13(1): 011001 (9 pages).
S.G. Chopski, N. Murad, C.S. Fox, R. Stevens, and A.L. Throckmorton. “Mechanical Circulatory Support of the Right Ventricle for Adult Patients with Heart Failure.” ASAIO J 2019 2019; 65(2): 106-116.
2018
C.S. Fox, S.G. Chopski, N. Murad, P.E. Allaire, R. Mentzer Jr., J. Rossano, F. Arabia, and A.L. Throckmorton. "Hybrid Continuous Flow Total Artificial Heart.” Artificial Organs 2018; 42(5): 500-509.
S.E. Cassel, C.S. Fox, K. Fox, M. Sahni, R. Dulman, K. Chung, R. Stevens, and A.L. Throckmorton. “Implantable Roller Pump for Heart-Failure Induced Lymphedema. Biomedical Journal of Scientific and Technical Research 2018; 3(2): 1-6.
J. Hernandez, S.G. Chopski, W.B. Moskowitz, S. Lee, and A.L. Throckmorton. “Externally Applied Compression Therapy for Fontan Patients.” Transl Pediatr 2018; 7(1):14-22.
2017
S.G. Chopski, W.B. Moskowitz, R.M. Stevens, and A.L. Throckmorton. "Mechanical Circulatory Support for Patients with Congenital Heart Disease." Artificial Organs 2017; 41(1): E1-E14.
S.G. Chopski, W.B. Moskowitz, R.M. Stevens, and A.L. Throckmorton. "Mechanical Circulatory Support for Patients with Congenital Heart Disease." Artificial Organs 2017; 41(1): E1-E14.
2016
S.G. Chopski, C.S. Fox, K.L. McKenna, M.L. Riddle, D.H. Kafagy, R.M. Stevens, and A.L. Throckmorton. “Physics-Driven Impeller Designs for a Novel Intravascular Blood Pump for Patients with Congenital Heart Disease.” Med Eng Phys 2016; 38(7): 622-632.
A.L. Throckmorton, S.M. Patel-Raman, C.S. Fox, and E.J. Bass. “Beyond the VAD: Human Factors, Decision Making and Personalized Medicine for Mechanically Assisted Circulation in the 21st Century.” Artificial Organs 2016;40(6):539-548.
A.L. Throckmorton, S.G. Chopski, S. Birewar, T. Joa, R. Stevens, and J.Y. Kresh. “Vortical Flow Characteristics of Mechanical Cavopulmonary Assistance: Pre- and Post-Swirl Dynamics.” Technology and Health Care 2016; 24: 627-638.
S.G. Chopski, C.S. Fox, M.L. Riddle, K.L. McKenna, J. Patel, J. Rozolis, and A.L. Throckmorton. “Pressure-Flow Experimental Performance Testing of New Intravascular Blood Pump Designs for Fontan Patients.” Artificial Organs 2016;40(3):233-42.
2015
C.S. Fox, K.L. McKenna, P.E. Allaire, R.M. Mentzer, Jr., and A.L. Throckmorton. “The Total Artificial Heart - Past, Current, and Future.” J Cardiac Surgery 2015; 30(11): 856-64.
A. Abbate, A.L. Throckmorton, and E.J. Bass. "A Formal Task Analytic Approach to Medical Device Alarm Troubleshooting Instructions." IEEE Transactions on Human-Machine Systems 2015; 46(1): 53-65.
S.G. Chopski, O.M. Rangus, E.A. Downs, W.B. Moskowitz, and A.L. Throckmorton. “Three-Dimensional Laser Flow Measurements of a Patient-Specific Fontan Physiology with Mechanical Circulatory Assistance.” Artificial Organs 2015; 39(6): e67-e78.
S.G. Chopski, O.M. Rangus, C.S. Fox, W.B. Moskowitz, and A.L. Throckmorton. “Stereo-PIV Measurements of a Patient-Specific Fontan Physiology using Novel Pressure Augmentation Stents.” Artificial Organs 2015; 39(3): 228-36.
D.H. Kafagy, T.W. Dwyer, K.L. McKenna, J.P. Mulles, S.G. Chopski, W.B. Moskowitz, and A.L. Throckmorton. “Simulations and Experiments in the Design of Axial Blood Pumps for Patients with Complex Congenital Cardiac Malformations.” Artificial Organs 2015; 39(1): 34-42.
2014
S.G. Chopski, O.M. Rangus, C.S. Fox, W.B. Moskowitz, and A.L. Throckmorton. "Stereo-PIV Measurements of a Patient-Specific Fontan Physiology using Novel Pressure Augmentation Stents." Artificial Organs 2014, In press.
2013
A.L. Throckmorton, S.S. Bhavsar, S.G. Chopski, and W.B. Moskowitz. "Pneumatically-Driven External Pressure Applicator to Augment Fontan Hemodynamics: Preliminary Findings." Transl Pediatr 2013; 2(4): 148-153. Accepted "As-is" for publication.
A.L. Throckmorton, S.A. Tahir, S. Lopes, O.M. Rangus, and M.G. Sciolino. "Steady and Transient Flow Analysis of a Magnetically Levitated Pediatric VAD: Time Varying Boundary Conditions." Int J Artif Organs 2013; 36(10): 693 - 699.
A.L. Throckmorton, S. Lopez-Isaza, and W.B. Moskowitz. "Dual-Blood Pump Support for Mechanical Assistance of the Fontan Physiology." Artificial Organs 2012, Artificial Organs 2013; 37(6): 513-22.
S.A. Tahir, W.B. Moskowitz, and A.L. Throckmorton. "Numerical Analysis of Protective Cage Geometries for Mechanical Cavopulmonary Assistance in a Patient-Specific Fontan Physiology." J Med Biol Eng 2013; 33(3): 257-262.
2012
E.A. Downs, W.B. Moskowitz, and A.L. Throckmorton. "Steady Flow Analysis of Mechanical Cavopulmonary Assistance in MRI-Derived Patient-Specific Fontan Configurations," Artificial Organs 2012; 36(11): 972-80.
A.L. Throckmorton, E.A. Downs, J.A. Hazelwood, J.O. Monroe, and S.G. Chopski. "Twisted Cardiovascular Cages for Intravascular Axial Flow Blood Pumps to Support the Fontan Physiology." Int J Artif Organs 2012; 35(5): 360-368.
A.L. Throckmorton, M.G. Sciolino, E.A. Downs, R.S. Saxman, S. Lopez-Isaza, and W.B. Moskowitz. "Controlled Pitch-Adjustment of Impeller Blades for an Intravascular Blood Pump." ASAIO J 2012; 58(4): 382-389.
2011
S.G. Chopski, E. Downs, C.M. Haggerty, A.P. Yoganathan, and A.L. Throckmorton. "PIV Measurements of an Idealized Total Cavopulmonary Connection with Mechanical Circulatory Assistance." Artificial Organs 2011; 35(11): 1052-1064.
A.L. Throckmorton, J.P. Carr, S.A. Tahir, R. Tate, E.A. Downs, S.S. Bhavsar, Y. Wu, J.D. Grizzard, and W.B. Moskowitz. "Mechanical Cavopulmonary Assistance of a Patient-Specific Fontan Physiology: Numerical Simulations, Lumped Parameter Modeling, and Suction Experiments." Artificial Organs 2011; 35(11): 1036-1047.
A.L. Throckmorton, J.Y. Kapadia, S.G. Chopski, S.S. Bhavsar, W.B. Moskowitz, S.D. Gullquist, J.J. Gangemi, C.M. Haggerty, and A.P. Yoganathan. "Numerical, Hydraulic, and Hemolytic Evaluation of an Intravascular Axial Flow Blood Pump to Mechanically Support Fontan Patients." Ann Biomed Engr 2011; 39(1): 324-336.
A.L. Throckmorton, J.Y. Kapadia, J.P. Carr, C.M. Powell, R.D. Tate, and D.V. Traynham. "Flexible Impeller Pump for Intravascular Cavopulmonary Assistance of the Fontan Physiology." Cardiovascular Engineering and Technology 2011; 1(4): 244-255.
2010
A.L. Throckmorton, T.M. Wittenschlaeger, J.Y. Kapadia, T.J. Medina, H.Q. Hoang, and S.S. Bhavsar. "Filament Support Spindle for an Intravascular Cavopulmonary Assist Device." Artificial Organs 2010; 34(11): 1039-1044.
S.S. Bhavsar, W.B. Moskowitz, and A.L. Throckmorton. "Interaction of an Idealized Cavopulmonary Circulation with Mechanical Circulatory Assist using an Intravascular Rotary Blood Pump." Artificial Organs 2010; 34(10): 816-827.
1.J.Y. Kapadia, K.C. Pierce, A.K. Poupore, and A.L. Throckmorton. "Hydraulic Testing of Intravascular Axial Flow Blood Pump Designs with a Protective Cage of Filaments for Mechanical Cavopulmonary Assist." ASAIO J 2010; 56: 17-23.
2009
S.S. Bhavsar, J.Y. Kapadia, S.G. Chopski, and A.L. Throckmorton. "Intravascular Mechanical Cavopulmonary Assistance for Patients with Failing Fontan Physiology." Artificial Organs 2009; 33(11): 977-987.
A.L. Throckmorton and R.A. Kishore. "Design of a Protective Cage of Filaments for an Axial Flow Blood Pump for Intravascular Cavopulmonary Assist." Artificial Organs 2009; 33(8): 611-621.
2008
A.L. Throckmorton, J. Kapadia, and D. Madduri. "Mechanical Axial Flow Blood Pump to Support the Cavopulmonary Circulation." Int J Artif Organs 2008; 31(11): 970-982.
A.L. Throckmortonand S.G. Chopski. "Pediatric Circulatory Support Systems: Current Strategies and Future Directions. Biventricular and Univentricular Mechanical Assistance." ASAIO J 2008; 54: 591-497.
A.L. Throckmorton and A. Untaroiu. "CFD Analysis of a Mag-Lev Ventricular Assist Device for Infants and Children: Fourth Generation Design." ASAIO J 2008; 54: 423-431.
A.L. Throckmorton, K.K. Ballman, C.D. Myers, S.H. Frankel, J.W. Brown, and M.D. Rodefeld. "Performance of an Expandable Propeller Pump for Cavopulmonary Assist in a Univentricular Fontan Circulation." Ann Thorac Surg 2008; 86: 1343-47.
2007
A.L. Throckmorton, C.D. Myers, K.K. Ballman, S.H. Frankel, K. Litwak, and M.D. Rodefeld. "Mechanical Cavopulmonary Assist for the Univentricular Fontan Circulation using a Novel Folding Propeller Blood Pump." ASAIO J 2007; 53: 734-741.
A.L. Throckmorton, A. Untaroiu, P.E. Allaire, H.G. Wood, D.S. Lim, M.A. McCulloch, and D.B. Olsen. "Numerical Design and Experimental Hydraulic Testing of an Axial Flow VAD for Infants and Children." ASAIO J 2007; 53: 754-761.
A.L. Throckmorton, A. Untaroiu, D.S. Lim, H.G. Wood, and P.E. Allaire. "Fluid Force Predictions and Experimental Measurements for a Magnetically Levitated Pediatric VAD." Artificial Organs 2007; 31(5): 359-368.
2005
A. Untaroiu, H.G. Wood, P.E. Allaire, A.L. Throckmorton, S.W. Day, S.M. Patel, Ellman, C.G. Tribble, and D.B. Olsen. "Computational Design and Experimental Testing of a Novel Axial Flow LVAD" ASAIO J 2005; 51: 702-710.
A.L. Throckmorton, D.S. Lim, M.A. McCulloch, W. Jiang, X. Song, P.E. Allaire, H.G. Wood, and D.B. Olsen. "Computational Design and Experimental Performance Testing of an Axial Flow Pediatric VAD." ASAIO J 2005; 51: 629-635.
S.M. Patel, A.L. Throckmorton, A. Untaroiu, P.E. Allaire, H.G. Wood, and D.B. Olsen."The Status of Failure and Reliability Testing of Artificial Blood Pumps." ASAIO J 2005; 51: 440-451.
A. Untaroiu,A.L. Throckmorton, H.G. Wood, P.E. Allaire, and D.B. Olsen. "Numerical and Experimental Analysis of an Axial Flow LVAD: The Influence of the Diffuser on the Overall Pump Performance." Artificial Organs 2005; 29(7): 581-91.
S.M. Patel, P.E. Allaire, H.G. Wood, A.L. Throckmorton, C.G. Tribble, and D.B. Olsen. "Methods of Failure and Reliability Assessment of Mechanical Heart Pumps." Artificial Organs 2005; 29(1): 15-25\. Recognized as one of the top 10 articles viewed online in 2005 at Blackwell Synergy Pub.
H.G. Wood,A.L. Throckmorton, A. Untaroiu, and X. Song. "The Medical Physics of Ventricular Assist Devices." Rep. Prog. Phys. 2005; 68: 1-32\. Recognized as one of the most frequently downloaded papers of 2005 by the journal.
2004
X. Song,A.L. Throckmorton, H.G. Wood, and D.B. Olsen. "Transient and Quasi-steady CFD Studies of a Left Ventricular Assist Device." ASAIO J 2004; 50: 410-417.
A.L. Throckmorton, A. Untaroiu, P.E. Allaire, H.G. Wood, G.P. Matherne, D.S. Lim, B.B. Peeler, and D.B. Olsen. "Computational Analysis of an Axial Flow Pediatric Ventricular Assist Device." Artificial Organs 2004; 28(10): 881-891.
X. Song, A.L. Throckmorton, H.G. Wood, J.F. Antaki, and D.B. Olsen. "Quantitative Evaluation of Blood Damage in a Centrifugal VAD by Computational Fluid Dynamics." J Fluids Engineering 2004; 126: 410-418.
X. Song, H.G. Wood, P.E. Allaire, A. Untaroiu, S.W. Day, A.L. Throckmorton, and D.B. Olsen. "Design and Transient CFD Study of a Continuous Axial Flow VAD." ASAIO J 2004; 50: 215-224.
2003
X. Song, A.L. Throckmorton, H.G. Wood, J.F. Antaki, and D.B. Olsen. "CFD Prediction of Blood Damage in a Centrifugal Pump." Artificial Organs 2003; 27(10): 938-941.
A.L. Throckmorton, H.G. Wood, S.W. Day, X. Song, P.C. Click, P.E. Allaire, and D.B. Olsen. "Design of a Continuous Flow Pediatric Ventricular Assist Device." Int J Artif Organs 2003; 26(11): 1015-31.